Question By: Weight loss medications, also known as anti-obesity medications, are typically prescribed for individuals who struggle to lose weight through diet and exercise alone, especially when obesity-related health risks are present. The most commonly used weight loss medications are FDA-approved and work in various ways, such as suppressing appetite, increasing feelings of fullness, or reducing fat absorption.
Semaglutide (Wegovy and Ozempic) has become one of the most widely recognized weight loss medications. Originally developed to treat type 2 diabetes, semaglutide mimics a hormone called GLP-1 that regulates appetite and blood sugar, leading to significant weight loss when used in higher doses. Liraglutide (Saxenda) functions similarly and is another GLP-1 receptor agonist prescribed for weight management.
Phentermine-topiramate (Qsymia) is a combination drug that suppresses appetite and enhances satiety, making it effective for short-term and long-term weight loss. Naltrexone-bupropion (Contrave) is another combination that affects the central nervous system to reduce hunger and cravings. For those who need assistance with fat absorption, Orlistat (Alli or Xenical) prevents the digestion of fats in the gut, though it may cause gastrointestinal side effects.
Each medication works best when paired with lifestyle changes, including a healthy diet and physical activity. It’s important to consult with a healthcare provider before beginning any weight loss medication to determine the most suitable option based on individual health needs.
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